We can use urllib.parse to handle special characters. Here is an example:

import urllib.parse
user='user@host.mysql.database.azure.com'
 
password=urllib.parse.quote_plus("P@test")
host="host.mysql.database.azure.com"
database = "db"
 
connect_args={'ssl':{'fake_flag_to_enable_tls': True}}
 
connect_string = 'mysql+pymysql://{}:{}@{}/{}'.format(user,password,host,database)
 
 
engine = create_engine(connect_string, connect_args=connect_args, echo=False)